Google DeepMind launched AlphaGenome Atlas, a searchable database with AI-predicted effects of all 9 billion possible single DNA mutations on human genes across hundreds of cell types. The Atlas combines two models—AlphaGenome (predicting regulatory effects) and AlphaMissense (predicting protein changes)—into a single Impact Score (AVI) that works on both protein-coding and non-coding regions (98% of the genome). This breakthrough compresses impractical lab experimentation into instant lookups, accelerating genetic research and rare disease diagnosis; researchers can now explore comprehensive genomic variants via a web browser, already demonstrating utility in identifying causal mutations in rare disease cases.