This article presents Sean Jacobsohn's "Six Forces of Failure" framework, derived from analyzing 1,000+ failed products from global brands (Amazon Dash, Apple Newton, Sony Betamax, BlackBerry). The six failure factors are: poor product-market fit, fragile financial structure, ignoring customer needs, intense competitive traps, misaligned organizational culture, and inadequate execution. Thai SME founders and marketers should study this framework to avoid repeating costly mistakes in product development and market entry.